The downside was that for 400 years, science has grown up,...

The downside was that for 400 years, science has grown up, has arisen and developed as a purely materialist concept and avoided the subject of mind and consciousness, leaving it to the realm of religion. Only with the founding of quantum science in the early part of the 20th century have we realized that the Cartesian Duality is wrong, that body, mind, physicality do interact and they're interrelated.