All of the plants that we do not consider food that are safe for the human body to digest, we don't eat because they're sour and bitter. The reason why you don't eat Kentucky bluegrass or crabgrass is because it tastes sour and bitter.
The interesting thing about the miracle berry in chemo patients is that it actually straightens out their taste buds, whereas for you and I, it blocks our bitter and sour receptors. For them, it straightens them out to taste food as it normally tastes.