Collective human actions are transforming, even ravaging, the biosphere - perhaps irreversibly - through global warming and loss of biodiversity.
Given the scale of issues like global warming and epidemic disease, we shouldn't underestimate the importance of a can-do attitude to science rather than a can't-afford-it attitude.
The atmospheric CO2 concentration is rising - mainly due to the burning of fossil fuels. It's agreed that this build-up will, in itself, induce a long-term warming trend, superimposed on all the other complicated effects that make climate fluctuate.
The challenge of global warming should stimulate a whole raft of manifestly benign innovations - for conserving energy and generating it by 'clean' means (biofuels, innovative renewables, carbon sequestration, and nuclear fusion).