Despair is good. Despair can be the nadir of one life and the starting point of an ascent into another, better one.
Liberty is only valued when it is threatened, therefore it is the threat that highlights the value. We should be grateful to the Nadir, since they heighten the value of our liberty.
Los Angeles is often described as the nadir of vapidity, a smog-choked space cradle.
Man, if he compare himself with all that he can see, is at the zenith of power; but if he compare himself with all that he can conceive, he is at the nadir of weakness.